Dual-targeted and pH-sensitive Doxorubicin Prodrug-Microbubble Complex with Ultrasound for Tumor Treatment

In this study, we investigated the potential of a dual-targeted pH-sensitive doxorubicin prodrug-microbubble complex (DPMC) in ultrasound (US)-assisted antitumor therapy. The doxorubicin prodrug (DP) consists of a succinylated-heparin carrier conjugated with doxorubicin (DOX) via hydrazone linkage a...

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Detalles Bibliográficos
Autores principales: Luo, Wanxian, Wen, Ge, Yang, Li, Tang, Jiao, Wang, Jianguo, Wang, Jihui, Zhang, Shiyu, Zhang, Li, Ma, Fei, Xiao, Liling, Wang, Ying, Li, Yingjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327360/
https://www.ncbi.nlm.nih.gov/pubmed/28255342
http://dx.doi.org/10.7150/thno.16677

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