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11R-P53 and GM-CSF Expressing Oncolytic Adenovirus Target Cancer Stem Cells with Enhanced Synergistic Activity

Targeting cancer stem cells with oncolytic virus (OV) holds great potential for thorough elimination of cancer cells. Based on our previous studies, we here established 11R-P53 and mGM-CSF carrying oncolytic adenovirus (OAV) SG655-mGMP and investigated its therapeutic effect on hepatocellular carcin...

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Detalles Bibliográficos
Autores principales: Lv, Sai-qun, Ye, Zhen-long, Liu, Pin-yi, Huang, Yao, Li, Lin-fang, Liu, Hui, Zhu, Hai-li, Jin, Hua-jun, Qian, Qi-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327369/
https://www.ncbi.nlm.nih.gov/pubmed/28243324
http://dx.doi.org/10.7150/jca.16406