Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients

Background: Purpose of this study was to evaluate the contribution of the Extracellular-regulated protein kinase (ERK)-1/2 pathway to oncogenic signaling elicited by the tyrosine kinase receptor HER2 in Non-Small Cell Lung Cancer (NSCLC) and to assess the prognostic value of these oncoproteins in NS...

Descripción completa

Detalles Bibliográficos
Autores principales: Scrima, Marianna, Zito Marino, Federica, Oliveira, Duarte Mendes, Marinaro, Cinzia, La Mantia, Elvira, Rocco, Gaetano, De Marco, Carmela, Malanga, Donatella, De Rosa, Nicla, Rizzuto, Antonia, Botti, Gerardo, Franco, Renato, Zoppoli, Pietro, Viglietto, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327372/
https://www.ncbi.nlm.nih.gov/pubmed/28243327
http://dx.doi.org/10.7150/jca.17093

Ejemplares similares

Ejemplares similares