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Identification of outcome-related driver mutations in cancer using conditional co-occurrence distributions

Previous methods proposed for the detection of cancer driver mutations have been based on the estimation of background mutation rate, impact on protein function, or network influence. In this paper, we instead focus on those factors influencing patient survival. To this end, an approximation of the...

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Detalles Bibliográficos
Autores principales: Treviño, Victor, Martínez-Ledesma, Emmanuel, Tamez-Peña, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327384/
https://www.ncbi.nlm.nih.gov/pubmed/28240231
http://dx.doi.org/10.1038/srep43350