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Identification of outcome-related driver mutations in cancer using conditional co-occurrence distributions
Previous methods proposed for the detection of cancer driver mutations have been based on the estimation of background mutation rate, impact on protein function, or network influence. In this paper, we instead focus on those factors influencing patient survival. To this end, an approximation of the...
Autores principales: | Treviño, Victor, Martínez-Ledesma, Emmanuel, Tamez-Peña, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327384/ https://www.ncbi.nlm.nih.gov/pubmed/28240231 http://dx.doi.org/10.1038/srep43350 |
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