TRPA1 mediated aggravation of allergic contact dermatitis induced by DINP and regulated by NF-κB activation

The possible pathogenic role and mechanism of Di-iso-nonyl phthalate (DINP) in allergic dermatitis is still controversial. This work has shown that oral exposure to DINP exacerbated allergic dermatitis tissue lesions in FITC-sensitized mice. The lesions was accompanied by an enhancement of TRPA1 exp...

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Detalles Bibliográficos
Autores principales: Kang, Jun, Ding, Yong, Li, Baizhan, Liu, Hong, Yang, Xu, Chen, Mingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327402/
https://www.ncbi.nlm.nih.gov/pubmed/28240277
http://dx.doi.org/10.1038/srep43586

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