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Characterization of the CD177 interaction with the ANCA antigen proteinase 3

Proteinase 3 is a serine protease found in neutrophil granules and on the extracellular neutrophil membrane (mPR3). mPR3 is a major antigen for anti-neutrophil cytoplasmic antibodies (PR3-ANCAs), autoantibodies causing fatal autoimmune diseases. In most individuals, a subpopulation of neutrophils al...

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Detalles Bibliográficos
Autores principales:	Jerke, Uwe, Marino, Stephen F., Daumke, Oliver, Kettritz, Ralph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327412/ https://www.ncbi.nlm.nih.gov/pubmed/28240246 http://dx.doi.org/10.1038/srep43328

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