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miR-21 deficiency inhibits osteoclast function and prevents bone loss in mice
MicroRNAs emerge as critical post-transcriptional regulators in bone metabolism. We have previously reported in vitro that miR-21 promotes osteogenesis, while studies have also revealed miR-21 as a regulator of osteoclastogenesis and a promoter of osteoclast differentiation in vitro. However, in viv...
Autores principales: | Hu, Cheng-Hu, Sui, Bing-Dong, Du, Fang-Ying, Shuai, Yi, Zheng, Chen-Xi, Zhao, Pan, Yu, Xiao-Rui, Jin, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327426/ https://www.ncbi.nlm.nih.gov/pubmed/28240263 http://dx.doi.org/10.1038/srep43191 |
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