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Amyloid plaque structure and cell surface interactions of β-amyloid fibrils revealed by electron tomography

The deposition of amyloid fibrils as plaques is a key feature of several neurodegenerative diseases including in particular Alzheimer’s. This disease is characterized, if not provoked, by amyloid aggregates formed from Aβ peptide that deposit inside the brain or are toxic to neuronal cells. We here...

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Detalles Bibliográficos
Autores principales: Han, Shen, Kollmer, Marius, Markx, Daniel, Claus, Stephanie, Walther, Paul, Fändrich, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327471/
https://www.ncbi.nlm.nih.gov/pubmed/28240273
http://dx.doi.org/10.1038/srep43577