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Amyloid plaque structure and cell surface interactions of β-amyloid fibrils revealed by electron tomography
The deposition of amyloid fibrils as plaques is a key feature of several neurodegenerative diseases including in particular Alzheimer’s. This disease is characterized, if not provoked, by amyloid aggregates formed from Aβ peptide that deposit inside the brain or are toxic to neuronal cells. We here...
Autores principales: | Han, Shen, Kollmer, Marius, Markx, Daniel, Claus, Stephanie, Walther, Paul, Fändrich, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327471/ https://www.ncbi.nlm.nih.gov/pubmed/28240273 http://dx.doi.org/10.1038/srep43577 |
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