Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy

Seizure-driven brain damage in epilepsy accumulates over time, especially in the hippocampus, which can lead to sclerosis, cognitive decline, and death. Excitotoxicity is the prevalent model to explain ictal neurodegeneration. Current labeling technologies cannot distinguish between excitotoxicity a...

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Detalles Bibliográficos
Autores principales: Leal-Campanario, Rocio, Alarcon-Martinez, Luis, Rieiro, Hector, Martinez-Conde, Susana, Alarcon-Martinez, Tugba, Zhao, Xiuli, LaMee, Jonathan, Popp, Pamela J. Osborn, Calhoun, Michael E., Arribas, Juan I., Schlegel, Alexander A., Stasi, Leandro L. Di, Rho, Jong M., Inge, Landon, Otero-Millan, Jorge, Treiman, David M., Macknik, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327474/
https://www.ncbi.nlm.nih.gov/pubmed/28240297
http://dx.doi.org/10.1038/srep43276

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