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ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastoma
Glioblastoma is associated with poor survival and a high recurrence rate in patients due to inevitable uncontrolled infiltrative tumor growth. The elucidation of the molecular mechanisms may offer opportunities to prevent relapses. In this study we investigated the role of the activating transcripti...
Autores principales: | Guenzle, Jessica, Wolf, Louisa J, Garrelfs, Nicklas W C, Goeldner, Jonathan M, Osterberg, Nadja, Schindler, Cora R, Saavedra, Joseph E, Weyerbrock, Astrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327503/ https://www.ncbi.nlm.nih.gov/pubmed/28250971 http://dx.doi.org/10.1038/cddiscovery.2017.6 |
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