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MINT: a multivariate integrative method to identify reproducible molecular signatures across independent experiments and platforms

BACKGROUND: Molecular signatures identified from high-throughput transcriptomic studies often have poor reliability and fail to reproduce across studies. One solution is to combine independent studies into a single integrative analysis, additionally increasing sample size. However, the different pro...

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Detalles Bibliográficos
Autores principales: Rohart, Florian, Eslami, Aida, Matigian, Nicholas, Bougeard, Stéphanie, Lê Cao, Kim-Anh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327533/
https://www.ncbi.nlm.nih.gov/pubmed/28241739
http://dx.doi.org/10.1186/s12859-017-1553-8