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Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report

BACKGROUND: Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. Early detection and institution of anti-tuberculosis medications can be life-saving...

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Autores principales: Haque, Wasim Md. Mohosin Ul, Shuvo, Md. Erfanur Rahman, Rahim, Muhammad Abdur, Mitra, Palash, Samad, Tabassum, Haque, Jalaluddin Ashraful
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327568/
https://www.ncbi.nlm.nih.gov/pubmed/28241857
http://dx.doi.org/10.1186/s13104-017-2434-y
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author Haque, Wasim Md. Mohosin Ul
Shuvo, Md. Erfanur Rahman
Rahim, Muhammad Abdur
Mitra, Palash
Samad, Tabassum
Haque, Jalaluddin Ashraful
author_facet Haque, Wasim Md. Mohosin Ul
Shuvo, Md. Erfanur Rahman
Rahim, Muhammad Abdur
Mitra, Palash
Samad, Tabassum
Haque, Jalaluddin Ashraful
author_sort Haque, Wasim Md. Mohosin Ul
collection PubMed
description BACKGROUND: Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. Early detection and institution of anti-tuberculosis medications can be life-saving. CASE PRESENTATION: A 23-year-old Bengali man presented with prolonged fever, weight loss, hepatosplenomegaly, pancytopenia and altered liver function. He had high erythrocyte sedimentation rate, positive tuberculin test, granuloma in liver biopsy, and haemophagocytosis was evidenced by histopathological examination of bone marrow. He recovered with anti-tuberculosis therapy. CONCLUSION: This case demonstrates that consideration of tuberculosis as an underlying cause of haemophagocytic syndrome could be rewarding and life-saving in this rapidly fatal condition.
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spelling pubmed-53275682017-03-03 Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report Haque, Wasim Md. Mohosin Ul Shuvo, Md. Erfanur Rahman Rahim, Muhammad Abdur Mitra, Palash Samad, Tabassum Haque, Jalaluddin Ashraful BMC Res Notes Case Report BACKGROUND: Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. Early detection and institution of anti-tuberculosis medications can be life-saving. CASE PRESENTATION: A 23-year-old Bengali man presented with prolonged fever, weight loss, hepatosplenomegaly, pancytopenia and altered liver function. He had high erythrocyte sedimentation rate, positive tuberculin test, granuloma in liver biopsy, and haemophagocytosis was evidenced by histopathological examination of bone marrow. He recovered with anti-tuberculosis therapy. CONCLUSION: This case demonstrates that consideration of tuberculosis as an underlying cause of haemophagocytic syndrome could be rewarding and life-saving in this rapidly fatal condition. BioMed Central 2017-02-27 /pmc/articles/PMC5327568/ /pubmed/28241857 http://dx.doi.org/10.1186/s13104-017-2434-y Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Haque, Wasim Md. Mohosin Ul
Shuvo, Md. Erfanur Rahman
Rahim, Muhammad Abdur
Mitra, Palash
Samad, Tabassum
Haque, Jalaluddin Ashraful
Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report
title Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report
title_full Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report
title_fullStr Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report
title_full_unstemmed Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report
title_short Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report
title_sort haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327568/
https://www.ncbi.nlm.nih.gov/pubmed/28241857
http://dx.doi.org/10.1186/s13104-017-2434-y
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