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Transcription factor family‐specific DNA shape readout revealed by quantitative specificity models

Transcription factors (TFs) achieve DNA‐binding specificity through contacts with functional groups of bases (base readout) and readout of structural properties of the double helix (shape readout). Currently, it remains unclear whether DNA shape readout is utilized by only a few selected TF families...

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Detalles Bibliográficos
Autores principales:	Yang, Lin, Orenstein, Yaron, Jolma, Arttu, Yin, Yimeng, Taipale, Jussi, Shamir, Ron, Rohs, Remo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327724/ https://www.ncbi.nlm.nih.gov/pubmed/28167566 http://dx.doi.org/10.15252/msb.20167238

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