Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures

Copy number alteration (CNA) profiling of human tumors has revealed recurrent patterns of DNA amplifications and deletions across diverse cancer types. These patterns are suggestive of conserved selection pressures during tumor evolution but cannot be fully explained by known oncogenes and tumor sup...

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Detalles Bibliográficos
Autores principales: Graham, Nicholas A, Minasyan, Aspram, Lomova, Anastasia, Cass, Ashley, Balanis, Nikolas G, Friedman, Michael, Chan, Shawna, Zhao, Sophie, Delgado, Adrian, Go, James, Beck, Lillie, Hurtz, Christian, Ng, Carina, Qiao, Rong, ten Hoeve, Johanna, Palaskas, Nicolaos, Wu, Hong, Müschen, Markus, Multani, Asha S, Port, Elisa, Larson, Steven M, Schultz, Nikolaus, Braas, Daniel, Christofk, Heather R, Mellinghoff, Ingo K, Graeber, Thomas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327725/
https://www.ncbi.nlm.nih.gov/pubmed/28202506
http://dx.doi.org/10.15252/msb.20167159

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