Reaction of Several Aminopyrimidines With Formaldehyde

Formaldehyde has been shown to react with 2-aminopyrimidine (II) and 2-(methylamino) pyrimidine (V) at room temperature to give the corresponding methylol derivatives or the corresponding methylenebis(aminopyrimidines). The reaction of formaldehyde with 2-amino-4,6-dichloro-5-methylpyrimidine (VII)...

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Detalles Bibliográficos
Autor principal: McLeod, Gerald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: [Gaithersburg, MD] : U.S. Dept. of Commerce, National Institute of Standards and Technology 1962
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327744/
http://dx.doi.org/10.6028/jres.066A.007
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author McLeod, Gerald L.
author_facet McLeod, Gerald L.
author_sort McLeod, Gerald L.
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description Formaldehyde has been shown to react with 2-aminopyrimidine (II) and 2-(methylamino) pyrimidine (V) at room temperature to give the corresponding methylol derivatives or the corresponding methylenebis(aminopyrimidines). The reaction of formaldehyde with 2-amino-4,6-dichloro-5-methylpyrimidine (VII) and also its failure to react with 2-(dimethylamino)pyrimidine (IX) are cited as evidence that the pyrimidine ring is not involved in the reaction.
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spelling pubmed-53277442023-06-15 Reaction of Several Aminopyrimidines With Formaldehyde McLeod, Gerald L. J Res Natl Bur Stand A Phys Chem Article Formaldehyde has been shown to react with 2-aminopyrimidine (II) and 2-(methylamino) pyrimidine (V) at room temperature to give the corresponding methylol derivatives or the corresponding methylenebis(aminopyrimidines). The reaction of formaldehyde with 2-amino-4,6-dichloro-5-methylpyrimidine (VII) and also its failure to react with 2-(dimethylamino)pyrimidine (IX) are cited as evidence that the pyrimidine ring is not involved in the reaction. [Gaithersburg, MD] : U.S. Dept. of Commerce, National Institute of Standards and Technology 1962 1962-02-01 /pmc/articles/PMC5327744/ http://dx.doi.org/10.6028/jres.066A.007 Text en https://creativecommons.org/publicdomain/zero/1.0/ The Journal of Research of the National Bureau of Standards Section A is a publication of the U.S. Government. The papers are in the public domain and are not subject to copyright in the United States. Articles from J Res may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.
spellingShingle Article
McLeod, Gerald L.
Reaction of Several Aminopyrimidines With Formaldehyde
title Reaction of Several Aminopyrimidines With Formaldehyde
title_full Reaction of Several Aminopyrimidines With Formaldehyde
title_fullStr Reaction of Several Aminopyrimidines With Formaldehyde
title_full_unstemmed Reaction of Several Aminopyrimidines With Formaldehyde
title_short Reaction of Several Aminopyrimidines With Formaldehyde
title_sort reaction of several aminopyrimidines with formaldehyde
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327744/
http://dx.doi.org/10.6028/jres.066A.007
work_keys_str_mv AT mcleodgeraldl reactionofseveralaminopyrimidineswithformaldehyde

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