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Pulling a Ligase out of a “HAT”: pCAF Mediates Ubiquitination of the Class II Transactivator

The Class II Transactivator (CIITA) is essential to the regulation of Major Histocompatibility Class II (MHC II) genes transcription. As the “master regulator” of MHC II transcription, CIITA regulation is imperative and requires various posttranslational modifications (PTMs) in order to facilitate i...

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Detalles Bibliográficos
Autores principales: Morgan, Julie E., Greer, Susanna F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327758/
https://www.ncbi.nlm.nih.gov/pubmed/28286521
http://dx.doi.org/10.1155/2017/8093813

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