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Pulling a Ligase out of a “HAT”: pCAF Mediates Ubiquitination of the Class II Transactivator
The Class II Transactivator (CIITA) is essential to the regulation of Major Histocompatibility Class II (MHC II) genes transcription. As the “master regulator” of MHC II transcription, CIITA regulation is imperative and requires various posttranslational modifications (PTMs) in order to facilitate i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327758/ https://www.ncbi.nlm.nih.gov/pubmed/28286521 http://dx.doi.org/10.1155/2017/8093813 |