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Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study

The outcome of patients suffering from out-of-hospital cardiac arrest (OHCA) is very poor, and postresuscitation comorbidities increase long-term mortality. This study aims to analyze new-onset postresuscitation comorbidities in patients who survived from OHCA for over one year. The Taiwan National...

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Autores principales: Su, Chih-Pei, Wu, Jr-Hau, Yang, Mei-Chueh, Liao, Ching-Hui, Hsu, Hsiu-Ying, Chang, Chin-Fu, Lan, Shou-Jen, Chu, Chiao-Lee, Lin, Yan-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327773/
https://www.ncbi.nlm.nih.gov/pubmed/28286775
http://dx.doi.org/10.1155/2017/9259182
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author Su, Chih-Pei
Wu, Jr-Hau
Yang, Mei-Chueh
Liao, Ching-Hui
Hsu, Hsiu-Ying
Chang, Chin-Fu
Lan, Shou-Jen
Chu, Chiao-Lee
Lin, Yan-Ren
author_facet Su, Chih-Pei
Wu, Jr-Hau
Yang, Mei-Chueh
Liao, Ching-Hui
Hsu, Hsiu-Ying
Chang, Chin-Fu
Lan, Shou-Jen
Chu, Chiao-Lee
Lin, Yan-Ren
author_sort Su, Chih-Pei
collection PubMed
description The outcome of patients suffering from out-of-hospital cardiac arrest (OHCA) is very poor, and postresuscitation comorbidities increase long-term mortality. This study aims to analyze new-onset postresuscitation comorbidities in patients who survived from OHCA for over one year. The Taiwan National Health Insurance (NHI) Database was used in this study. Study and comparison groups were created to analyze the risk of suffering from new-onset postresuscitation comorbidities from 2011 to 2012 (until December 31, 2013). The study group included 1,346 long-term OHCA survivors; the comparison group consisted of 4,038 matched non-OHCA patients. Demographics, patient characteristics, and risk of suffering comorbidities (using Cox proportional hazards models) were analyzed. We found that urinary tract infections (n = 225, 16.72%), pneumonia (n = 206, 15.30%), septicemia (n = 184, 13.67%), heart failure (n = 111, 8.25%) gastrointestinal hemorrhage (n = 108, 8.02%), epilepsy or recurrent seizures (n = 98, 7.28%), and chronic kidney disease (n = 62, 4.61%) were the most common comorbidities. Furthermore, OHCA survivors were at much higher risk (than comparison patients) of experiencing epilepsy or recurrent seizures (HR = 20.83; 95% CI: 12.24–35.43), septicemia (HR = 8.98; 95% CI: 6.84–11.79), pneumonia (HR = 5.82; 95% CI: 4.66–7.26), and heart failure (HR = 4.88; 95% CI: 3.65–6.53). Most importantly, most comorbidities occurred within the first half year after OHCA.
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spelling pubmed-53277732017-03-12 Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study Su, Chih-Pei Wu, Jr-Hau Yang, Mei-Chueh Liao, Ching-Hui Hsu, Hsiu-Ying Chang, Chin-Fu Lan, Shou-Jen Chu, Chiao-Lee Lin, Yan-Ren Biomed Res Int Research Article The outcome of patients suffering from out-of-hospital cardiac arrest (OHCA) is very poor, and postresuscitation comorbidities increase long-term mortality. This study aims to analyze new-onset postresuscitation comorbidities in patients who survived from OHCA for over one year. The Taiwan National Health Insurance (NHI) Database was used in this study. Study and comparison groups were created to analyze the risk of suffering from new-onset postresuscitation comorbidities from 2011 to 2012 (until December 31, 2013). The study group included 1,346 long-term OHCA survivors; the comparison group consisted of 4,038 matched non-OHCA patients. Demographics, patient characteristics, and risk of suffering comorbidities (using Cox proportional hazards models) were analyzed. We found that urinary tract infections (n = 225, 16.72%), pneumonia (n = 206, 15.30%), septicemia (n = 184, 13.67%), heart failure (n = 111, 8.25%) gastrointestinal hemorrhage (n = 108, 8.02%), epilepsy or recurrent seizures (n = 98, 7.28%), and chronic kidney disease (n = 62, 4.61%) were the most common comorbidities. Furthermore, OHCA survivors were at much higher risk (than comparison patients) of experiencing epilepsy or recurrent seizures (HR = 20.83; 95% CI: 12.24–35.43), septicemia (HR = 8.98; 95% CI: 6.84–11.79), pneumonia (HR = 5.82; 95% CI: 4.66–7.26), and heart failure (HR = 4.88; 95% CI: 3.65–6.53). Most importantly, most comorbidities occurred within the first half year after OHCA. Hindawi Publishing Corporation 2017 2017-02-13 /pmc/articles/PMC5327773/ /pubmed/28286775 http://dx.doi.org/10.1155/2017/9259182 Text en Copyright © 2017 Chih-Pei Su et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Su, Chih-Pei
Wu, Jr-Hau
Yang, Mei-Chueh
Liao, Ching-Hui
Hsu, Hsiu-Ying
Chang, Chin-Fu
Lan, Shou-Jen
Chu, Chiao-Lee
Lin, Yan-Ren
Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study
title Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study
title_full Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study
title_fullStr Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study
title_full_unstemmed Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study
title_short Demographics and Clinical Features of Postresuscitation Comorbidities in Long-Term Survivors of Out-of-Hospital Cardiac Arrest: A National Follow-Up Study
title_sort demographics and clinical features of postresuscitation comorbidities in long-term survivors of out-of-hospital cardiac arrest: a national follow-up study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327773/
https://www.ncbi.nlm.nih.gov/pubmed/28286775
http://dx.doi.org/10.1155/2017/9259182
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