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Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model
BACKGROUND: Proteases may play an important role in the development of chronic obstructive pulmonary disease and emphysema in response to cigarette smoke exposure (CSE). The current study was designed to investigate the expression of matrix metalloproteinase (MMP)-8, MMP-9, MMP-12, tissue inhibitor...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327908/ https://www.ncbi.nlm.nih.gov/pubmed/28260878 http://dx.doi.org/10.2147/COPD.S110520 |