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Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model

BACKGROUND: Proteases may play an important role in the development of chronic obstructive pulmonary disease and emphysema in response to cigarette smoke exposure (CSE). The current study was designed to investigate the expression of matrix metalloproteinase (MMP)-8, MMP-9, MMP-12, tissue inhibitor...

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Detalles Bibliográficos
Autores principales:	Sun, Jiawei, Bao, Jie, Shi, Yanan, Zhang, Bin, Yuan, Lindong, Li, Junhong, Zhang, Lihai, Sun, Mo, Zhang, Ling, Sun, Wuzhuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327908/ https://www.ncbi.nlm.nih.gov/pubmed/28260878 http://dx.doi.org/10.2147/COPD.S110520

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