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Pharmaceutical characterization of novel tenofovir liposomal formulations for enhanced oral drug delivery: in vitro pharmaceutics and Caco-2 permeability investigations
Tenofovir, currently marketed as the prodrug tenofovir disoproxil fumarate, is used clinically to treat patients with HIV/AIDS. The oral bioavailability of tenofovir is relatively low, limiting its clinical effectiveness. Encapsulation of tenofovir within modified long-circulating liposomes would de...
Autores principales: | Spinks, Crystal B, Zidan, Ahmed S, Khan, Mansoor A, Habib, Muhammad J, Faustino, Patrick J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327912/ https://www.ncbi.nlm.nih.gov/pubmed/28260952 http://dx.doi.org/10.2147/CPAA.S119875 |
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