Cargando…

Antiproliferation effect of imatinib mesylate on MCF7, T-47D tumorigenic and MCF 10A nontumorigenic breast cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF genes

Recent cancer molecular therapies are targeting main functional molecules to control applicable process of cancer cells. Attractive targets are established by receptor tyrosine kinases, such as platelet-derived growth factor receptors (PDGFRs) and c-Kit as mostly irregular signaling, which is due to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kadivar, Ali, Kamalidehghan, Behnam, Akbari Javar, Hamid, Karimi, Benyamin, Sedghi, Reihaneh, Noordin, Mohamed Ibrahim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327915/ https://www.ncbi.nlm.nih.gov/pubmed/28260860 http://dx.doi.org/10.2147/DDDT.S124102

Ejemplares similares

Antiproliferative effects of imatinib mesylate on ZR-75-1 and MDA-MB-231 cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF expression
por: Kadivar, Ali, et al.
Publicado: (2019)

Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet
por: Kadivar, Ali, et al.
Publicado: (2015)

Molecular Characterization of PDGFR-α/PDGF-A and c-KIT/SCF in Gliosarcomas
por: Reis, Rui M., et al.
Publicado: (2005)

PDGFR in PDGF-BB/PDGFR Signaling Pathway Does Orchestrates Osteogenesis in a Temporal Manner
por: Wang, Fangqian, et al.
Publicado: (2023)

A fibronectin peptide redirects PDGF-BB/PDGFR complexes to macropinocytosis-like internalization and augments PDGF-BB survival signals
por: Zhu, Jia, et al.
Publicado: (2013)

Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis
por: Wang, Xingqi, et al.
Publicado: (2016)

Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury
por: Yao, Fei, et al.
Publicado: (2022)

Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression
por: Tsioumpekou, Maria, et al.
Publicado: (2020)

Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression: Erratum
por: Tsioumpekou, Maria, et al.
Publicado: (2020)

Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer’s disease
por: Smyth, Leon C. D., et al.
Publicado: (2022)

Elevated PDGF‐BB from Bone Impairs Hippocampal Vasculature by Inducing PDGFRβ Shedding from Pericytes
por: Liu, Guanqiao, et al.
Publicado: (2023)

Endothelial PDGF-BB/PDGFR-β signaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formation
por: Cui, Zhuang, et al.
Publicado: (2022)

PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly
Publicado: (1992)

Antiproliferation Activity and Apoptotic Mechanism of Soursop (Annona muricata L.) Leaves Extract and Fractions on MCF7 Breast Cancer Cells
por: Hadisaputri, Yuni Elsa, et al.
Publicado: (2021)

Comprehensive Dissection of PDGF-PDGFR Signaling Pathways in PDGFR Genetically Defined Cells
por: Wu, Erxi, et al.
Publicado: (2008)

PDGF/PDGFR effects in osteosarcoma and the “add-on” strategy
por: Xu, Jie, et al.
Publicado: (2018)

Preparation and Characterization of a Gastric Floating Dosage Form of Capecitabine
por: Taghizadeh Davoudi, Ehsan, et al.
Publicado: (2013)

Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in vivo through suppression of PDGFR-β
por: Ohishi, Jun, et al.
Publicado: (2013)

Activity and expression of progesterone metabolizing 5α-reductase, 20α-hydroxysteroid oxidoreductase and 3α(β)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells
por: Wiebe, John P, et al.
Publicado: (2003)

Periorbital edema secondary to imatinib mesylate
por: McClelland, Collin M, et al.
Publicado: (2010)

Cutaneous adverse effects of imatinib mesylate
por: Dogu, Mehmet Hilmi, et al.
Publicado: (2015)

Endothelial progenitor cells promote viability and nerve regenerative ability of mesenchymal stem cells through PDGF-BB/PDGFR-β signaling
por: Fang, Jiafeng, et al.
Publicado: (2020)

Effects of ginsenoside Rb1 on second-degree burn wound healing and FGF-2/PDGF-BB/PDGFR-β pathway modulation
por: Zhang, Li, et al.
Publicado: (2021)

Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signalling
por: Sarri, Niki, et al.
Publicado: (2022)

Tanacetum polycephalum (L.) Schultz-Bip. Induces Mitochondrial-Mediated Apoptosis and Inhibits Migration and Invasion in MCF7 Cells
por: Karimian, Hamed, et al.
Publicado: (2014)

Low plasma PDGF-BB levels are associated with estradiol in postmenopausal osteoporosis: PDGF-BB mediated by estradiol in women
por: Tang, Lanhua, et al.
Publicado: (2017)

miR-34c inhibits PDGF-BB-induced HAVSMCs phenotypic transformation and proliferation via PDGFR-β/SIRT1 pathway
por: Wan, Wei-feng, et al.
Publicado: (2021)

PDGF-BB signaling via PDGFR-β regulates the maturation of blood vessels generated upon vasculogenic differentiation of dental pulp stem cells
por: Zhang, Zhaocheng, et al.
Publicado: (2022)

PDGF/PDGFR: A Possible Molecular Target in Scleroderma Fibrosis
por: Paolini, Chiara, et al.
Publicado: (2022)

Imatinib Mesylate-Induced Hyperpigmentation of the Nose and Palate
por: Song, Hyo Sang, et al.
Publicado: (2014)

Imatinib mesylate resistance and mutations: An Indian experience
por: Srivastava, Shweta, et al.
Publicado: (2013)

Lichenoid drug eruption due to imatinib mesylate
por: Bhatia, Anuradha, et al.
Publicado: (2015)

The teratogenic effects of imatinib mesylate on rat fetuses
por: El Gendy, M.M., et al.
Publicado: (2015)

Exacerbation of Psoriasis after Imatinib Mesylate Treatment
por: Shim, Joon Ho, et al.
Publicado: (2016)

Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44(+)/CD24(−/low)): an in vitro study
por: Ahmadipour, Fatemeh, et al.
Publicado: (2015)

Platelet-Derived Growth Factor (PDGF)/PDGF Receptors (PDGFR) Axis as Target for Antitumor and Antiangiogenic Therapy
por: Raica, Marius, et al.
Publicado: (2010)

Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways
por: Yu, Yi-Chu, et al.
Publicado: (2013)

Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement
por: Jin, Yuqin, et al.
Publicado: (2020)

Osteoclasts Control Osteoblast Chemotaxis via PDGF-BB/PDGF Receptor Beta Signaling
por: Sanchez-Fernandez, Maria Arantzazu, et al.
Publicado: (2008)

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_ruqk0t2cb6al1ftjja2k7dnbd1