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Rapid and simultaneous detection of common aneuploidies by quadruplex real-time polymerase chain reaction combined with melting curve analysis

BACKGROUND: During the prenatal period, the number variation of chromosomes 13, 18, 21, X and Y accounts for more than 80% of the clinically significant chromosomal abnormalities diagnosed. Rapid tests for prenatal diagnosis of these abnormalities can improve pregnancy management and alleviate paren...

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Detalles Bibliográficos
Autores principales:	Lou, Jiwu, Sun, Manna, Zhao, Ying, Ji, Zhisong, Liu, Fenghua, Li, Dongzhi, Xu, Wanfang, Lin, Yangyang, Liu, Yanhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328249/ https://www.ncbi.nlm.nih.gov/pubmed/28241016 http://dx.doi.org/10.1371/journal.pone.0171886

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