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Systemic abnormalities associated with retinal vein occlusion in young patients

OBJECTIVES: To study the systemic abnormalities associated with retinal vein occlusion in patients aged ≤50 years with a particular emphasis on atherosclerotic diseases and thrombophilic disorders. METHODS: Medical charts of patients, aged ≤50 years whose diagnoses were retinal vein occlusions durin...

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Autores principales: Sinawat, Suthasinee, Bunyavee, Chavisa, Ratanapakorn, Tanapat, Sinawat, Supat, Laovirojjanakul, Wipada, Yospaiboon, Yosanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328302/
https://www.ncbi.nlm.nih.gov/pubmed/28260858
http://dx.doi.org/10.2147/OPTH.S128341
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author Sinawat, Suthasinee
Bunyavee, Chavisa
Ratanapakorn, Tanapat
Sinawat, Supat
Laovirojjanakul, Wipada
Yospaiboon, Yosanan
author_facet Sinawat, Suthasinee
Bunyavee, Chavisa
Ratanapakorn, Tanapat
Sinawat, Supat
Laovirojjanakul, Wipada
Yospaiboon, Yosanan
author_sort Sinawat, Suthasinee
collection PubMed
description OBJECTIVES: To study the systemic abnormalities associated with retinal vein occlusion in patients aged ≤50 years with a particular emphasis on atherosclerotic diseases and thrombophilic disorders. METHODS: Medical charts of patients, aged ≤50 years whose diagnoses were retinal vein occlusions during the period 1995–2015 were retrospectively reviewed. The primary outcome was the number of systemic abnormalities associated with these patients. Secondary outcomes included types of retinal vein occlusion and sites of occlusion. RESULTS: Atherosclerotic diseases were the most common systemic abnormalities associated with retinal vein occlusion and accounted for 55.1% of the patients in the study. Hypertension in 27.55%, diabetes mellitus in 16.33%, and 5.1% with dyslipidemia were noted. The number of thrombophilic disorders seemed to be less than expected and were noted in only 5.1%. Other systemic abnormalities included viral hepatitis infection, systemic lupus erythematosus, and acquired immunodeficiency syndrome. Oral contraceptives were used by some patients. CONCLUSION: Atherosclerotic diseases remained the most commonly associated systemic diseases in the majority of these patients. Approach to these patients should include a screening for hypertension, diabetes mellitus, and lipid abnormalities. Thrombophilia should also be considered where no obvious atherosclerotic diseases are found or if the patient is <40 years old, a history of thrombosis or a family history of thrombosis is possible.
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spelling pubmed-53283022017-03-03 Systemic abnormalities associated with retinal vein occlusion in young patients Sinawat, Suthasinee Bunyavee, Chavisa Ratanapakorn, Tanapat Sinawat, Supat Laovirojjanakul, Wipada Yospaiboon, Yosanan Clin Ophthalmol Original Research OBJECTIVES: To study the systemic abnormalities associated with retinal vein occlusion in patients aged ≤50 years with a particular emphasis on atherosclerotic diseases and thrombophilic disorders. METHODS: Medical charts of patients, aged ≤50 years whose diagnoses were retinal vein occlusions during the period 1995–2015 were retrospectively reviewed. The primary outcome was the number of systemic abnormalities associated with these patients. Secondary outcomes included types of retinal vein occlusion and sites of occlusion. RESULTS: Atherosclerotic diseases were the most common systemic abnormalities associated with retinal vein occlusion and accounted for 55.1% of the patients in the study. Hypertension in 27.55%, diabetes mellitus in 16.33%, and 5.1% with dyslipidemia were noted. The number of thrombophilic disorders seemed to be less than expected and were noted in only 5.1%. Other systemic abnormalities included viral hepatitis infection, systemic lupus erythematosus, and acquired immunodeficiency syndrome. Oral contraceptives were used by some patients. CONCLUSION: Atherosclerotic diseases remained the most commonly associated systemic diseases in the majority of these patients. Approach to these patients should include a screening for hypertension, diabetes mellitus, and lipid abnormalities. Thrombophilia should also be considered where no obvious atherosclerotic diseases are found or if the patient is <40 years old, a history of thrombosis or a family history of thrombosis is possible. Dove Medical Press 2017-02-23 /pmc/articles/PMC5328302/ /pubmed/28260858 http://dx.doi.org/10.2147/OPTH.S128341 Text en © 2017 Sinawat et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Sinawat, Suthasinee
Bunyavee, Chavisa
Ratanapakorn, Tanapat
Sinawat, Supat
Laovirojjanakul, Wipada
Yospaiboon, Yosanan
Systemic abnormalities associated with retinal vein occlusion in young patients
title Systemic abnormalities associated with retinal vein occlusion in young patients
title_full Systemic abnormalities associated with retinal vein occlusion in young patients
title_fullStr Systemic abnormalities associated with retinal vein occlusion in young patients
title_full_unstemmed Systemic abnormalities associated with retinal vein occlusion in young patients
title_short Systemic abnormalities associated with retinal vein occlusion in young patients
title_sort systemic abnormalities associated with retinal vein occlusion in young patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328302/
https://www.ncbi.nlm.nih.gov/pubmed/28260858
http://dx.doi.org/10.2147/OPTH.S128341
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