Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages

The diarrheal pathogen Clostridium difficile consists of at least six distinct evolutionary lineages. The RT017 lineage is anomalous, as strains only express toxin B, compared to strains from other lineages that produce toxins A and B and, occasionally, binary toxin. Historically, RT017 initially wa...

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Detalles Bibliográficos
Autores principales: Cairns, M. D., Preston, M. D., Hall, C. L., Gerding, D. N., Hawkey, P. M., Kato, H., Kim, H., Kuijper, E. J., Lawley, T. D., Pituch, H., Reid, S., Kullin, B., Riley, T. V., Solomon, K., Tsai, P. J., Weese, J. S., Stabler, R. A., Wren, B. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328454/
https://www.ncbi.nlm.nih.gov/pubmed/28031436
http://dx.doi.org/10.1128/JCM.01296-16

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