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In Vivo Fitness Adaptations of Colistin-Resistant Acinetobacter baumannii Isolates to Oxidative Stress
The loss of fitness in colistin-resistant (CR) Acinetobacter baumannii was investigated using longitudinal isolates from the same patient. Early CR isolates were outcompeted by late CR isolates for growth in broth and survival in the lungs of mice. Fitness loss was associated with an increased susce...
Autores principales: | Jones, Crystal L., Singh, Shweta S., Alamneh, Yonas, Casella, Leila G., Ernst, Robert K., Lesho, Emil P., Waterman, Paige E., Zurawski, Daniel V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328574/ https://www.ncbi.nlm.nih.gov/pubmed/27993849 http://dx.doi.org/10.1128/AAC.00598-16 |
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