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Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein
Diabetes is linked to an increased risk for colorectal cancer, but the mechanistic underpinnings of this clinically important effect are unclear. Here we describe an interaction between the microtubule motor cytoplasmic dynein, the adenomatous polyposis coli tumor suppressor protein (APC), and glyco...
Autores principales: | Gao, Feng J., Shi, Liang, Hines, Timothy, Hebbar, Sachin, Neufeld, Kristi L., Smith, Deanna S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328618/ https://www.ncbi.nlm.nih.gov/pubmed/28057765 http://dx.doi.org/10.1091/mbc.E16-07-0555 |
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