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Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46–IFT56 as well as on its nuclear localization signal

Cilia function as cellular antennae to sense and transduce extracellular signals. A number of proteins are specifically localized in cilia. Anterograde and retrograde ciliary protein trafficking are mediated by the IFT-B and IFT-A complexes in concert with kinesin-2 and dynein-2 motors, respectively...

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Detalles Bibliográficos
Autores principales: Funabashi, Teruki, Katoh, Yohei, Michisaka, Saki, Terada, Masaya, Sugawa, Maho, Nakayama, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328621/
https://www.ncbi.nlm.nih.gov/pubmed/28077622
http://dx.doi.org/10.1091/mbc.E16-09-0648