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α-amanitin resistance in Drosophila melanogaster: A genome-wide association approach

We investigated the mechanisms of mushroom toxin resistance in the Drosophila Genetic Reference Panel (DGRP) fly lines, using genome-wide association studies (GWAS). While Drosophila melanogaster avoids mushrooms in nature, some lines are surprisingly resistant to α-amanitin—a toxin found solely in...

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Detalles Bibliográficos
Autores principales: Mitchell, Chelsea L., Latuszek, Catrina E., Vogel, Kara R., Greenlund, Ian M., Hobmeier, Rebecca E., Ingram, Olivia K., Dufek, Shannon R., Pecore, Jared L., Nip, Felicia R., Johnson, Zachary J., Ji, Xiaohui, Wei, Hairong, Gailing, Oliver, Werner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328632/
https://www.ncbi.nlm.nih.gov/pubmed/28241077
http://dx.doi.org/10.1371/journal.pone.0173162