Cargando…

CXCL12 protects pancreatic β-cells from oxidative stress by a Nrf2-induced increase in catalase expression and activity

Due to intrinsically low levels of antioxidant enzyme expression and activity, insulin producing pancreatic β-cells are particularly susceptible to free radical attack. In diabetes mellitus, which is accompanied by high levels of oxidative stress, this feature of β-cells significantly contributes to...

Descripción completa

Detalles Bibliográficos
Autores principales: DINIĆ, Svetlana, GRDOVIĆ, Nevena, USKOKOVIĆ, Aleksandra, ĐORĐEVIĆ, Miloš, MIHAILOVIĆ, Mirjana, JOVANOVIĆ, Jelena Arambašić, POZNANOVIĆ, Goran, VIDAKOVIĆ, Melita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328787/
https://www.ncbi.nlm.nih.gov/pubmed/27840391
http://dx.doi.org/10.2183/pjab.92.436