Melatonin Mediates Protective Effects against Kainic Acid-Induced Neuronal Death through Safeguarding ER Stress and Mitochondrial Disturbance

Kainic acid (KA)-induced neuronal death is linked to mitochondrial dysfunction and ER stress. Melatonin is known to protect hippocampal neurons from KA-induced apoptosis, but the exact mechanisms underlying melatonin protective effects against neuronal mitochondria disorder and ER stress remain unce...

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Detalles Bibliográficos
Autores principales: Xue, Feixiao, Shi, Cai, Chen, Qingjie, Hang, Weijian, Xia, Liangtao, Wu, Yue, Tao, Sophia Z., Zhou, Jie, Shi, Anbing, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329003/
https://www.ncbi.nlm.nih.gov/pubmed/28293167
http://dx.doi.org/10.3389/fnmol.2017.00049

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