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Extracellular Acidification Inhibits the ROS-Dependent Formation of Neutrophil Extracellular Traps
The inflammatory microenvironment is commonly characterized by extracellular acidosis (pH < 7.35). Sensitivity to pH, CO(2) or bicarbonate concentrations allows neutrophils to react to changes in their environment and to detect inflamed areas in the tissue. One important antimicrobial effector me...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329032/ https://www.ncbi.nlm.nih.gov/pubmed/28293240 http://dx.doi.org/10.3389/fimmu.2017.00184 |