Studies at the Ionizable Position of Cephalosporins and Penicillins: Hydroxamates as Substitutes for the Traditional Carboxylate Group

Classically, β-lactams need an ionizable group to potentiate antibacterial activity. Sets of cephalosporins and penicillins featuring different substituted hydroxamates in place of the traditional carboxylate group have been synthesized and tested for antibiotic activity. Many of the compounds exhib...

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Detalles Bibliográficos
Autores principales: Majewski, Mark W., Miller, Patricia A., Miller, Marvin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329033/
https://www.ncbi.nlm.nih.gov/pubmed/27999444
http://dx.doi.org/10.1038/ja.2016.149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329033/
https://www.ncbi.nlm.nih.gov/pubmed/27999444
http://dx.doi.org/10.1038/ja.2016.149

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