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The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer

OBJECTIVE: To report our experience for the initial management of patients with newly diagnosed bladder tumours using our team approach for each case and using an aggressive extended transurethral resection of bladder tumour (TURBT) in order to investigate the real need for a routine ‘second-look’ c...

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Autores principales: Atta, Mohamed Adel, Kotb, Ahmed Fouad, Sharafeldeen, Mohamed, Elabbady, Ahmed, Hashad, Mohamed Mohie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329698/
https://www.ncbi.nlm.nih.gov/pubmed/28275520
http://dx.doi.org/10.1016/j.aju.2016.10.003
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author Atta, Mohamed Adel
Kotb, Ahmed Fouad
Sharafeldeen, Mohamed
Elabbady, Ahmed
Hashad, Mohamed Mohie
author_facet Atta, Mohamed Adel
Kotb, Ahmed Fouad
Sharafeldeen, Mohamed
Elabbady, Ahmed
Hashad, Mohamed Mohie
author_sort Atta, Mohamed Adel
collection PubMed
description OBJECTIVE: To report our experience for the initial management of patients with newly diagnosed bladder tumours using our team approach for each case and using an aggressive extended transurethral resection of bladder tumour (TURBT) in order to investigate the real need for a routine ‘second-look’ cystoscopy in the current era. PATIENTS AND METHODS: The study included 50 consecutive patients admitted to the urology department, of our tertiary care centre, for management of newly diagnosed bladder cancer. Exclusion criteria included past history of bladder tumour, palpable mass on bimanual examination under anaesthesia, presence of residual tumour at the end of resection, and patients with tumours of the bladder dome as thorough resection is difficult to achieve in this area without an attendant risk. Patients that had pathologically confirmed carcinoma in situ were also excluded. White-light cystoscopy was used in all of the cases. Extended TURBT was defined as resection of the whole tumour, resection of the tumour base and 1 cm of apparently normal bladder wall around the circumference of the tumour. RESULTS: The median (range) age of the patients was 52 (39–60) years. After initial TURBT, 10 patients (20%) were identified as having muscle-invasive bladder cancer. Of the remaining 40 patients, three had low-grade Ta disease, and so second biopsies were not taken. The remaining 37 patients had T1, grade 2–3 disease and none of them had evident residual disease at the site of tumour resection. CONCLUSION: Re-staging TURBT could be safely omitted for select groups of patients. An experienced surgeon and teamwork, together with an extended TURBT can accurately achieve complete tumour resection, with accurate tumour staging, on initial resection.
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spelling pubmed-53296982017-03-08 The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer Atta, Mohamed Adel Kotb, Ahmed Fouad Sharafeldeen, Mohamed Elabbady, Ahmed Hashad, Mohamed Mohie Arab J Urol Original Article OBJECTIVE: To report our experience for the initial management of patients with newly diagnosed bladder tumours using our team approach for each case and using an aggressive extended transurethral resection of bladder tumour (TURBT) in order to investigate the real need for a routine ‘second-look’ cystoscopy in the current era. PATIENTS AND METHODS: The study included 50 consecutive patients admitted to the urology department, of our tertiary care centre, for management of newly diagnosed bladder cancer. Exclusion criteria included past history of bladder tumour, palpable mass on bimanual examination under anaesthesia, presence of residual tumour at the end of resection, and patients with tumours of the bladder dome as thorough resection is difficult to achieve in this area without an attendant risk. Patients that had pathologically confirmed carcinoma in situ were also excluded. White-light cystoscopy was used in all of the cases. Extended TURBT was defined as resection of the whole tumour, resection of the tumour base and 1 cm of apparently normal bladder wall around the circumference of the tumour. RESULTS: The median (range) age of the patients was 52 (39–60) years. After initial TURBT, 10 patients (20%) were identified as having muscle-invasive bladder cancer. Of the remaining 40 patients, three had low-grade Ta disease, and so second biopsies were not taken. The remaining 37 patients had T1, grade 2–3 disease and none of them had evident residual disease at the site of tumour resection. CONCLUSION: Re-staging TURBT could be safely omitted for select groups of patients. An experienced surgeon and teamwork, together with an extended TURBT can accurately achieve complete tumour resection, with accurate tumour staging, on initial resection. Elsevier 2016-11-26 /pmc/articles/PMC5329698/ /pubmed/28275520 http://dx.doi.org/10.1016/j.aju.2016.10.003 Text en © 2016 Arab Association of Urology. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Atta, Mohamed Adel
Kotb, Ahmed Fouad
Sharafeldeen, Mohamed
Elabbady, Ahmed
Hashad, Mohamed Mohie
The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer
title The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer
title_full The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer
title_fullStr The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer
title_full_unstemmed The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer
title_short The value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer
title_sort value of extended good quality transurethral resection of bladder tumour in the treatment of the newly diagnosed bladder cancer
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329698/
https://www.ncbi.nlm.nih.gov/pubmed/28275520
http://dx.doi.org/10.1016/j.aju.2016.10.003
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