Perinatal risk factors in newborns with gastrointestinal perforation

AIM: To investigate correlation of perinatal risk factors in newborns with gastrointestinal perforation (GIP). METHODS: Single-center retrospective cohort study was conducted between January 1990 and December 2012. Medical records on all newborns with GIP were reviewed (n = 35). Surgical records and...

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Autores principales: Prgomet, Sandra, Lukšić, Boris, Pogorelić, Zenon, Jurić, Ivo, Čapkun, Vesna, Arapović, Adela, Boban, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Retrospective Cohort Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329703/
https://www.ncbi.nlm.nih.gov/pubmed/28289509
http://dx.doi.org/10.4240/wjgs.v9.i2.46
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author Prgomet, Sandra
Lukšić, Boris
Pogorelić, Zenon
Jurić, Ivo
Čapkun, Vesna
Arapović, Adela
Boban, Nataša
author_facet Prgomet, Sandra
Lukšić, Boris
Pogorelić, Zenon
Jurić, Ivo
Čapkun, Vesna
Arapović, Adela
Boban, Nataša
author_sort Prgomet, Sandra
collection PubMed
description AIM: To investigate correlation of perinatal risk factors in newborns with gastrointestinal perforation (GIP). METHODS: Single-center retrospective cohort study was conducted between January 1990 and December 2012. Medical records on all newborns with GIP were reviewed (n = 35). Surgical records and histopathologic examination of all perforated intestine samples were also reviewed. RESULTS: The most common cause of GIP was necrotizing enterocolitis (51.4%). The most common site of perforation was large intestine. Mortality rate was 31%. Infants with GIP more frequently had very low birth weight (< 1500 g), especially birth weight below 10(th) percentile according to gestational age. Ponderal index was not differing between infants with GIP and control subjects. In infants with GIP anemia was more frequently found than in control group. CONCLUSION: GIP in newborns is mostly disease of infants with birth weight below 10(th) percentile according to gestational age. GIP occurs more often in infants with anemia.
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spelling pubmed-53297032017-03-13 Perinatal risk factors in newborns with gastrointestinal perforation Prgomet, Sandra Lukšić, Boris Pogorelić, Zenon Jurić, Ivo Čapkun, Vesna Arapović, Adela Boban, Nataša World J Gastrointest Surg Retrospective Cohort Study AIM: To investigate correlation of perinatal risk factors in newborns with gastrointestinal perforation (GIP). METHODS: Single-center retrospective cohort study was conducted between January 1990 and December 2012. Medical records on all newborns with GIP were reviewed (n = 35). Surgical records and histopathologic examination of all perforated intestine samples were also reviewed. RESULTS: The most common cause of GIP was necrotizing enterocolitis (51.4%). The most common site of perforation was large intestine. Mortality rate was 31%. Infants with GIP more frequently had very low birth weight (< 1500 g), especially birth weight below 10(th) percentile according to gestational age. Ponderal index was not differing between infants with GIP and control subjects. In infants with GIP anemia was more frequently found than in control group. CONCLUSION: GIP in newborns is mostly disease of infants with birth weight below 10(th) percentile according to gestational age. GIP occurs more often in infants with anemia. Baishideng Publishing Group Inc 2017-02-27 2017-02-27 /pmc/articles/PMC5329703/ /pubmed/28289509 http://dx.doi.org/10.4240/wjgs.v9.i2.46 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Retrospective Cohort Study
Prgomet, Sandra
Lukšić, Boris
Pogorelić, Zenon
Jurić, Ivo
Čapkun, Vesna
Arapović, Adela
Boban, Nataša
Perinatal risk factors in newborns with gastrointestinal perforation
title Perinatal risk factors in newborns with gastrointestinal perforation
title_full Perinatal risk factors in newborns with gastrointestinal perforation
title_fullStr Perinatal risk factors in newborns with gastrointestinal perforation
title_full_unstemmed Perinatal risk factors in newborns with gastrointestinal perforation
title_short Perinatal risk factors in newborns with gastrointestinal perforation
title_sort perinatal risk factors in newborns with gastrointestinal perforation
topic Retrospective Cohort Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329703/
https://www.ncbi.nlm.nih.gov/pubmed/28289509
http://dx.doi.org/10.4240/wjgs.v9.i2.46
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