Cargando…

L-carnitine protects C2C12 cells against mitochondrial superoxide overproduction and cell death

AIM: To identify and characterize the protective effect that L-carnitine exerted against an oxidative stress in C2C12 cells. METHODS: Myoblastic C2C12 cells were treated with menadione, a vitamin K analog that engenders oxidative stress, and the protective effect of L-carnitine (a nutrient involved...

Descripción completa

Detalles Bibliográficos
Autores principales:	Le Borgne, Françoise, Ravaut, Gaétan, Bernard, Arnaud, Demarquoy, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2017
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329717/ https://www.ncbi.nlm.nih.gov/pubmed/28289521 http://dx.doi.org/10.4331/wjbc.v8.i1.86

Ejemplares similares

Exploration of Lipid Metabolism in Relation with Plasma Membrane Properties of Duchenne Muscular Dystrophy Cells: Influence of L-Carnitine
por: Le Borgne, Françoise, et al.
Publicado: (2012)

Autism and carnitine: A possible link
por: Demarquoy, Caroline, et al.
Publicado: (2019)

Overproduction, Purification, and Stability of the Functionally Active Human Carnitine Acetyl Transferase
por: Giudice, Deborah, et al.
Publicado: (2022)

Superoxide overproduction and kidney fibrosis: a new animal model
por: Guimarães-Souza, Nadia Karina, et al.
Publicado: (2015)

Mitochondrial carnitine palmitoyl transferase-II inactivity aggravates lipid accumulation in rat hepatocarcinogenesis
por: Gu, Juan-Juan, et al.
Publicado: (2017)

Nifedipine protects against overproduction of superoxide anion by monocytes from patients with systemic sclerosis
por: Allanore, Yannick, et al.
Publicado: (2005)

Overproduction of superoxide dismutase and catalase confers cassava resistance to Tetranychus cinnabarinus
por: Lu, Fuping, et al.
Publicado: (2017)

Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts
por: Sin, Jon, et al.
Publicado: (2015)

Recombinant adenoviral microRNA-206 induces myogenesis in C2C12 cells
por: Zhang, Weiwei, et al.
Publicado: (2011)

Exogenous C(8)-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells
por: Chang, Yuli C., et al.
Publicado: (2018)

Expression and purification of TAT-fused carbonic anhydrase III and its effect on C2C12 cell apoptosis induced by hypoxia/reoxygenation
por: Shang, Xiliang, et al.
Publicado: (2012)

Efficacy and Safety of the Combination of Superoxide Dismutase, Alpha Lipoic Acid, Vitamin B12, and Carnitine for 12 Months in Patients with Diabetic Neuropathy
por: Didangelos, Triantafyllos, et al.
Publicado: (2020)

Mitochondrial pathway of the lysine demethylase 5C inhibitor CPI-455 in the Eca-109 esophageal squamous cell carcinoma cell line
por: Xue, Xiao-Jie, et al.
Publicado: (2021)

Failure of carnitine in improving hepatic nitrogen content in alcoholic and non‐alcoholic malnourished rats
por: Rodrigues, Luciana P, et al.
Publicado: (2010)

Superoxide Radicals in the Execution of Cell Death
por: Fujii, Junichi, et al.
Publicado: (2022)

Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction
por: El-Khoury, Riyad, et al.
Publicado: (2013)

Carnitine regulates myocardial metabolism by Peroxisome Proliferator-Activated Receptor-α (PPARα) in alcoholic cardiomyopathy
por: Jing, Ling, et al.
Publicado: (2011)

Significant Reduction of Murine Renal Ischemia-Reperfusion Cell Death Using the Immediate-Acting PrC-210 Reactive Oxygen Species Scavenger
por: Bath, Natalie M., et al.
Publicado: (2019)

An Overproduction of Scholars
Publicado: (1893)

Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence
por: Zhang, Huizhen, et al.
Publicado: (2021)

Fine-tuning mitochondrial activity in Yarrowia lipolytica for citrate overproduction
por: da Veiga Moreira, Jorgelindo, et al.
Publicado: (2021)

Effect of acetyl-L-carnitine on hypersensitivity in acute recurrent caerulein-induced pancreatitis and microglial activation along the brain’s pain circuitry
por: McIlwrath, Sabrina L, et al.
Publicado: (2021)

Aerobic Swim Training Restores Aortic Endothelial Function by Decreasing Superoxide Levels in Spontaneously Hypertensive Rats
por: Jordão, Camila P, et al.
Publicado: (2017)

Superoxide Dismutase Levels and Polymorphism (Ala16val) In Tuberculosis Patients with Diabetes Mellitus in Medan City
por: Sari, Mutiara Indah, et al.
Publicado: (2019)

TFAM deficiency in dendritic cells leads to mitochondrial dysfunction and enhanced antitumor immunity through cGAS-STING pathway
por: Lu, Tianqi, et al.
Publicado: (2023)

PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle
por: Novakova, Katerina, et al.
Publicado: (2022)

The Antitumor Effect of C-terminus of Hsp70-Interacting Protein via Degradation of c-Met in Small Cell Lung Cancer
por: Cho, Sung Ho, et al.
Publicado: (2017)

Isolinderalactone Induces Cell Death via Mitochondrial Superoxide- and STAT3-Mediated Pathways in Human Ovarian Cancer Cells
por: Rajina, Shakya, et al.
Publicado: (2020)

Manipulation of pathway regulation in Streptomyces globisporus for overproduction of the enediyne antitumor antibiotic C-1027
por: Chen, Yihua, et al.
Publicado: (2010)

Damaged mitochondria and overproduction of ROS in Fanconi anemia cells
por: Lyakhovich, Alex
Publicado: (2013)

Characterization of Cell Death Induced by Imine Analogs of Trans-Resveratrol: Induction of Mitochondrial Dysfunction and Overproduction of Reactive Oxygen Species Leading to, or Not, Apoptosis without the Increase in the S-Phase of the Cell Cycle
por: Ksila, Mohamed, et al.
Publicado: (2023)

Carnitines as Mitochondrial Modulators of Oocyte and Embryo Bioenergetics
por: Placidi, Martina, et al.
Publicado: (2022)

32219 Differences in cell death in methionine versus cysteine depletion
por: Wallis, Katherine F., et al.
Publicado: (2021)

Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity
por: Watanabe, S, et al.
Publicado: (2014)

Impact of high dose vitamin C on platelet function
por: Mohammed, Bassem M, et al.
Publicado: (2017)

Hydrogen-rich saline protects spermatogenesis and hematopoiesis in irradiated BALB/c mice
por: Chuai, Yunhai, et al.
Publicado: (2012)

Complement receptor 3 mediates renal protection in experimental C3 glomerulopathy
por: Barbour, Thomas D., et al.
Publicado: (2016)

Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence
por: Wang, Yongtao, et al.
Publicado: (2020)

(13)C Metabolic Flux Analysis for Systematic Metabolic Engineering of S. cerevisiae for Overproduction of Fatty Acids
por: Ghosh, Amit, et al.
Publicado: (2016)

Elucidation of Triacylglycerol Overproduction in the C(4) Bioenergy Crop Sorghum bicolor by Constraint-Based Analysis
por: Clark, Teresa J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a6f5s81g3fjve3eo2hvqtp7st1