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Left atrial appendage occlusion: A better alternative to anticoagulation?

Non-valvular atrial fibrillation is associated with a significantly increased risk of embolic stroke due to blood clot forming predominantly in the left atrial appendage (LAA). Preventive measures to avoid embolic events are permanent administration of anticoagulants or surgical closure of the LAA....

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Detalles Bibliográficos
Autores principales: Akin, Ibrahim, Nienaber, Christoph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329740/
https://www.ncbi.nlm.nih.gov/pubmed/28289527
http://dx.doi.org/10.4330/wjc.v9.i2.139
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author Akin, Ibrahim
Nienaber, Christoph A
author_facet Akin, Ibrahim
Nienaber, Christoph A
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description Non-valvular atrial fibrillation is associated with a significantly increased risk of embolic stroke due to blood clot forming predominantly in the left atrial appendage (LAA). Preventive measures to avoid embolic events are permanent administration of anticoagulants or surgical closure of the LAA. Various clinical trials provide evidence about safety, effectiveness and therapeutic success of LAA occlusion using various cardiac occluder devices. The use of such implants for interventional closure of the LAA is likely to become a valuable alternative for stroke prevention, especially in patients with contraindication for oral anticoagulation as safety, clinical benefit and cost-effectiveness of LAA occlusion has recently been demonstrated.
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spelling pubmed-53297402017-03-13 Left atrial appendage occlusion: A better alternative to anticoagulation? Akin, Ibrahim Nienaber, Christoph A World J Cardiol Minireviews Non-valvular atrial fibrillation is associated with a significantly increased risk of embolic stroke due to blood clot forming predominantly in the left atrial appendage (LAA). Preventive measures to avoid embolic events are permanent administration of anticoagulants or surgical closure of the LAA. Various clinical trials provide evidence about safety, effectiveness and therapeutic success of LAA occlusion using various cardiac occluder devices. The use of such implants for interventional closure of the LAA is likely to become a valuable alternative for stroke prevention, especially in patients with contraindication for oral anticoagulation as safety, clinical benefit and cost-effectiveness of LAA occlusion has recently been demonstrated. Baishideng Publishing Group Inc 2017-02-26 2017-02-26 /pmc/articles/PMC5329740/ /pubmed/28289527 http://dx.doi.org/10.4330/wjc.v9.i2.139 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Minireviews
Akin, Ibrahim
Nienaber, Christoph A
Left atrial appendage occlusion: A better alternative to anticoagulation?
title Left atrial appendage occlusion: A better alternative to anticoagulation?
title_full Left atrial appendage occlusion: A better alternative to anticoagulation?
title_fullStr Left atrial appendage occlusion: A better alternative to anticoagulation?
title_full_unstemmed Left atrial appendage occlusion: A better alternative to anticoagulation?
title_short Left atrial appendage occlusion: A better alternative to anticoagulation?
title_sort left atrial appendage occlusion: a better alternative to anticoagulation?
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329740/
https://www.ncbi.nlm.nih.gov/pubmed/28289527
http://dx.doi.org/10.4330/wjc.v9.i2.139
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