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Left atrial appendage occlusion: A better alternative to anticoagulation?
Non-valvular atrial fibrillation is associated with a significantly increased risk of embolic stroke due to blood clot forming predominantly in the left atrial appendage (LAA). Preventive measures to avoid embolic events are permanent administration of anticoagulants or surgical closure of the LAA....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329740/ https://www.ncbi.nlm.nih.gov/pubmed/28289527 http://dx.doi.org/10.4330/wjc.v9.i2.139 |
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author | Akin, Ibrahim Nienaber, Christoph A |
author_facet | Akin, Ibrahim Nienaber, Christoph A |
author_sort | Akin, Ibrahim |
collection | PubMed |
description | Non-valvular atrial fibrillation is associated with a significantly increased risk of embolic stroke due to blood clot forming predominantly in the left atrial appendage (LAA). Preventive measures to avoid embolic events are permanent administration of anticoagulants or surgical closure of the LAA. Various clinical trials provide evidence about safety, effectiveness and therapeutic success of LAA occlusion using various cardiac occluder devices. The use of such implants for interventional closure of the LAA is likely to become a valuable alternative for stroke prevention, especially in patients with contraindication for oral anticoagulation as safety, clinical benefit and cost-effectiveness of LAA occlusion has recently been demonstrated. |
format | Online Article Text |
id | pubmed-5329740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-53297402017-03-13 Left atrial appendage occlusion: A better alternative to anticoagulation? Akin, Ibrahim Nienaber, Christoph A World J Cardiol Minireviews Non-valvular atrial fibrillation is associated with a significantly increased risk of embolic stroke due to blood clot forming predominantly in the left atrial appendage (LAA). Preventive measures to avoid embolic events are permanent administration of anticoagulants or surgical closure of the LAA. Various clinical trials provide evidence about safety, effectiveness and therapeutic success of LAA occlusion using various cardiac occluder devices. The use of such implants for interventional closure of the LAA is likely to become a valuable alternative for stroke prevention, especially in patients with contraindication for oral anticoagulation as safety, clinical benefit and cost-effectiveness of LAA occlusion has recently been demonstrated. Baishideng Publishing Group Inc 2017-02-26 2017-02-26 /pmc/articles/PMC5329740/ /pubmed/28289527 http://dx.doi.org/10.4330/wjc.v9.i2.139 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Minireviews Akin, Ibrahim Nienaber, Christoph A Left atrial appendage occlusion: A better alternative to anticoagulation? |
title | Left atrial appendage occlusion: A better alternative to anticoagulation? |
title_full | Left atrial appendage occlusion: A better alternative to anticoagulation? |
title_fullStr | Left atrial appendage occlusion: A better alternative to anticoagulation? |
title_full_unstemmed | Left atrial appendage occlusion: A better alternative to anticoagulation? |
title_short | Left atrial appendage occlusion: A better alternative to anticoagulation? |
title_sort | left atrial appendage occlusion: a better alternative to anticoagulation? |
topic | Minireviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329740/ https://www.ncbi.nlm.nih.gov/pubmed/28289527 http://dx.doi.org/10.4330/wjc.v9.i2.139 |
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