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Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer
Conventional transbronchial needle aspiration (C-TBNA) is a minimally invasive technique used primarily in the diagnosis and staging of lung cancer. Currently lung cancer is mostly considered a disease of the elderly and the management of this disease in older patients is a growing concern. In this...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter Open
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329871/ https://www.ncbi.nlm.nih.gov/pubmed/28352839 http://dx.doi.org/10.1515/med-2016-0084 |
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author | Vitale, Carolina Galderisi, Antonio Maglio, Angelantonio Laperuta, Paolo Di Crescenzo, Rosa Maria Selleri, Carmine Molino, Antonio Vatrella, Alessandro |
author_facet | Vitale, Carolina Galderisi, Antonio Maglio, Angelantonio Laperuta, Paolo Di Crescenzo, Rosa Maria Selleri, Carmine Molino, Antonio Vatrella, Alessandro |
author_sort | Vitale, Carolina |
collection | PubMed |
description | Conventional transbronchial needle aspiration (C-TBNA) is a minimally invasive technique used primarily in the diagnosis and staging of lung cancer. Currently lung cancer is mostly considered a disease of the elderly and the management of this disease in older patients is a growing concern. In this study we aimed to assess the diagnostic yield and safety of C-TBNA in elderly patients. A retrospective review of 88 consecutive C-TBNA procedures for nodal staging in suspected or confirmed primary lung cancer or pathological confirmation in suspected advanced lung cancer was performed. Patients were divided into less than 70 (<70yrs) or 70 and older (≥70yrs) age groups for analysis. There were no significant differences either in the diagnostic yield (69% in patients aged < 70 yrs and 74% patients aged ≥ 70 yrs (p=0.5) nor in the complication rate (respectively 8.8% in patients aged < 70 yrs and 6.9% in patients aged ≥ 70 yrs (p=0.7) between the two age groups. Reported complications were minor bleeding and poor tolerance; no major complications were observed. Based on our experience, C-TBNA represents a useful and safe alternative procedure for the diagnosis and staging of lung cancer in elderly patients. |
format | Online Article Text |
id | pubmed-5329871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | De Gruyter Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-53298712017-03-28 Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer Vitale, Carolina Galderisi, Antonio Maglio, Angelantonio Laperuta, Paolo Di Crescenzo, Rosa Maria Selleri, Carmine Molino, Antonio Vatrella, Alessandro Open Med (Wars) Research Article Conventional transbronchial needle aspiration (C-TBNA) is a minimally invasive technique used primarily in the diagnosis and staging of lung cancer. Currently lung cancer is mostly considered a disease of the elderly and the management of this disease in older patients is a growing concern. In this study we aimed to assess the diagnostic yield and safety of C-TBNA in elderly patients. A retrospective review of 88 consecutive C-TBNA procedures for nodal staging in suspected or confirmed primary lung cancer or pathological confirmation in suspected advanced lung cancer was performed. Patients were divided into less than 70 (<70yrs) or 70 and older (≥70yrs) age groups for analysis. There were no significant differences either in the diagnostic yield (69% in patients aged < 70 yrs and 74% patients aged ≥ 70 yrs (p=0.5) nor in the complication rate (respectively 8.8% in patients aged < 70 yrs and 6.9% in patients aged ≥ 70 yrs (p=0.7) between the two age groups. Reported complications were minor bleeding and poor tolerance; no major complications were observed. Based on our experience, C-TBNA represents a useful and safe alternative procedure for the diagnosis and staging of lung cancer in elderly patients. De Gruyter Open 2016-11-19 /pmc/articles/PMC5329871/ /pubmed/28352839 http://dx.doi.org/10.1515/med-2016-0084 Text en © 2016 Carolina Vitale et al. http://creativecommons.org/licenses/by-nc-nd/3.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. |
spellingShingle | Research Article Vitale, Carolina Galderisi, Antonio Maglio, Angelantonio Laperuta, Paolo Di Crescenzo, Rosa Maria Selleri, Carmine Molino, Antonio Vatrella, Alessandro Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer |
title | Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer |
title_full | Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer |
title_fullStr | Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer |
title_full_unstemmed | Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer |
title_short | Diagnostic yield and safety of C-TBNA in elderly patients with lung cancer |
title_sort | diagnostic yield and safety of c-tbna in elderly patients with lung cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329871/ https://www.ncbi.nlm.nih.gov/pubmed/28352839 http://dx.doi.org/10.1515/med-2016-0084 |
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