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Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit

Acinetobacter baumannii, a non-fermenting Gram-negative bacterium, is a common pathogen in intensive care units (ICU) that is easily spread through contact and can cause nosocomial outbreaks. This study investigated the risk factors associated with outbreaks of pan-drug resistant Acinetobacter bauma...

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Autores principales: Ying, Qian, Qun, Li, Qinzhong, Liu, Mingliang, Chen, Hong, Chen, Ni, Zou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter Open 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329883/
https://www.ncbi.nlm.nih.gov/pubmed/28352851
http://dx.doi.org/10.1515/med-2016-0096
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author Ying, Qian
Qun, Li
Qinzhong, Liu
Mingliang, Chen
Hong, Chen
Ni, Zou
author_facet Ying, Qian
Qun, Li
Qinzhong, Liu
Mingliang, Chen
Hong, Chen
Ni, Zou
author_sort Ying, Qian
collection PubMed
description Acinetobacter baumannii, a non-fermenting Gram-negative bacterium, is a common pathogen in intensive care units (ICU) that is easily spread through contact and can cause nosocomial outbreaks. This study investigated the risk factors associated with outbreaks of pan-drug resistant Acinetobacter baumannii (PDR-Ab) infection by studying a suspected nosocomial outbreak in a comprehensive ICU in a teaching hospital in China, and discusses the effectiveness of current prevention and control measures. Pathogen detection methods involving pulsed field gel electrophoresis (PFGE) were employed to survey patients infected or colonized with PDR-Ab. An epidemiological investigation was conducted to determine the risk factors for infection or colonization with PDR-Ab between 1 October 2014 and 16 January 2015. The rate of PDR-Ab infection in the ICU was higher during the period from 1 October 2014 to 16 January 2015 than it was between 1 October 2013 and 16 January 2014. Only two cases were confirmed to have the same genotype. Risk factors were explored and the rate of infection was found to be controlled by interventions targeting these risk factors. A decrease in the number of infections was observed after multiple prevention and control measures were implemented, preventing the outbreak of a nosocomial infection.
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spelling pubmed-53298832017-03-28 Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit Ying, Qian Qun, Li Qinzhong, Liu Mingliang, Chen Hong, Chen Ni, Zou Open Med (Wars) Regular Article Acinetobacter baumannii, a non-fermenting Gram-negative bacterium, is a common pathogen in intensive care units (ICU) that is easily spread through contact and can cause nosocomial outbreaks. This study investigated the risk factors associated with outbreaks of pan-drug resistant Acinetobacter baumannii (PDR-Ab) infection by studying a suspected nosocomial outbreak in a comprehensive ICU in a teaching hospital in China, and discusses the effectiveness of current prevention and control measures. Pathogen detection methods involving pulsed field gel electrophoresis (PFGE) were employed to survey patients infected or colonized with PDR-Ab. An epidemiological investigation was conducted to determine the risk factors for infection or colonization with PDR-Ab between 1 October 2014 and 16 January 2015. The rate of PDR-Ab infection in the ICU was higher during the period from 1 October 2014 to 16 January 2015 than it was between 1 October 2013 and 16 January 2014. Only two cases were confirmed to have the same genotype. Risk factors were explored and the rate of infection was found to be controlled by interventions targeting these risk factors. A decrease in the number of infections was observed after multiple prevention and control measures were implemented, preventing the outbreak of a nosocomial infection. De Gruyter Open 2016-12-30 /pmc/articles/PMC5329883/ /pubmed/28352851 http://dx.doi.org/10.1515/med-2016-0096 Text en © 2016 Qian Ying et al. http://creativecommons.org/licenses/by-nc-nd/3.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
spellingShingle Regular Article
Ying, Qian
Qun, Li
Qinzhong, Liu
Mingliang, Chen
Hong, Chen
Ni, Zou
Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit
title Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit
title_full Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit
title_fullStr Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit
title_full_unstemmed Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit
title_short Investigation and control of a suspected nosocomial outbreak of pan-drug resistant Acinetobacter baumannii in an intensive care unit
title_sort investigation and control of a suspected nosocomial outbreak of pan-drug resistant acinetobacter baumannii in an intensive care unit
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329883/
https://www.ncbi.nlm.nih.gov/pubmed/28352851
http://dx.doi.org/10.1515/med-2016-0096
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