Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

BACKGROUND: An increased expression of Yes-associated protein (YAP1) has been shown to promote tumorigenesis in many cancer types including colon. However, the role of YAP1 in promoting colon tumorigenesis remains unclear. Here, we demonstrate that YAP1 expression is associated with M2 tumor-associa...

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Detalles Bibliográficos
Autores principales: Huang, Yan-Jiun, Yang, Ching-Kuo, Wei, Po-Li, Huynh, Thanh-Tuan, Whang-Peng, Jacqueline, Meng, Tzu-Ching, Hsiao, Michael, Tzeng, Yew-Ming, Wu, Alexander TH, Yen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329923/
https://www.ncbi.nlm.nih.gov/pubmed/28241877
http://dx.doi.org/10.1186/s13045-017-0421-3

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