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Middle East respiratory syndrome coronavirus: review of the current situation in the world

This article reviews the current epidemiology and clinical presentation of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and describes the preparedness plan of several countries. The MERS-CoV was first reported in 2012 and has since infected more than 1600 patients in 26 countrie...

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Autores principales: Shapiro, Michael, London, Beny, Nigri, Daniel, Shoss, Alon, Zilber, Eyal, Fogel, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329956/
https://www.ncbi.nlm.nih.gov/pubmed/28265443
http://dx.doi.org/10.1186/s40696-016-0019-2
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author Shapiro, Michael
London, Beny
Nigri, Daniel
Shoss, Alon
Zilber, Eyal
Fogel, Itay
author_facet Shapiro, Michael
London, Beny
Nigri, Daniel
Shoss, Alon
Zilber, Eyal
Fogel, Itay
author_sort Shapiro, Michael
collection PubMed
description This article reviews the current epidemiology and clinical presentation of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and describes the preparedness plan of several countries. The MERS-CoV was first reported in 2012 and has since infected more than 1600 patients in 26 countries, mostly in Saudi Arabia and the Middle East. The epidemiology of the infection is compatible with multiple introductions of the virus into humans from an animal reservoir, probably dromedary camels. The clinical presentation ranges from no symptoms to severe pneumonitis and respiratory failure. Most confirmed cases so far were part of MERS-CoV clusters in hospital settings, affecting mainly middle-aged men and patients with a chronic disease or immuno-suppressed status. There is no vaccine or anti-viral medication available. Viral epidemics can occur anywhere in today’s “global village”. MERS-CoV is a relatively new virus, and this work is intended to add to the still-sparse data on its epidemiology, modes of transmission, natural history, and clinical features as well as to describe the preparedness plan for MERS-CoV infection in several countries. Effective national and international preparedness plans are essential to predict and control outbreaks, improve patient management, and ensure global health security.
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spelling pubmed-53299562017-03-06 Middle East respiratory syndrome coronavirus: review of the current situation in the world Shapiro, Michael London, Beny Nigri, Daniel Shoss, Alon Zilber, Eyal Fogel, Itay Disaster Mil Med Review This article reviews the current epidemiology and clinical presentation of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and describes the preparedness plan of several countries. The MERS-CoV was first reported in 2012 and has since infected more than 1600 patients in 26 countries, mostly in Saudi Arabia and the Middle East. The epidemiology of the infection is compatible with multiple introductions of the virus into humans from an animal reservoir, probably dromedary camels. The clinical presentation ranges from no symptoms to severe pneumonitis and respiratory failure. Most confirmed cases so far were part of MERS-CoV clusters in hospital settings, affecting mainly middle-aged men and patients with a chronic disease or immuno-suppressed status. There is no vaccine or anti-viral medication available. Viral epidemics can occur anywhere in today’s “global village”. MERS-CoV is a relatively new virus, and this work is intended to add to the still-sparse data on its epidemiology, modes of transmission, natural history, and clinical features as well as to describe the preparedness plan for MERS-CoV infection in several countries. Effective national and international preparedness plans are essential to predict and control outbreaks, improve patient management, and ensure global health security. BioMed Central 2016-05-04 /pmc/articles/PMC5329956/ /pubmed/28265443 http://dx.doi.org/10.1186/s40696-016-0019-2 Text en © Shapiro et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Shapiro, Michael
London, Beny
Nigri, Daniel
Shoss, Alon
Zilber, Eyal
Fogel, Itay
Middle East respiratory syndrome coronavirus: review of the current situation in the world
title Middle East respiratory syndrome coronavirus: review of the current situation in the world
title_full Middle East respiratory syndrome coronavirus: review of the current situation in the world
title_fullStr Middle East respiratory syndrome coronavirus: review of the current situation in the world
title_full_unstemmed Middle East respiratory syndrome coronavirus: review of the current situation in the world
title_short Middle East respiratory syndrome coronavirus: review of the current situation in the world
title_sort middle east respiratory syndrome coronavirus: review of the current situation in the world
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329956/
https://www.ncbi.nlm.nih.gov/pubmed/28265443
http://dx.doi.org/10.1186/s40696-016-0019-2
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