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BJ-1108, a 6-Amino-2,4,5-trimethylpyridin-3-ol analogue, regulates differentiation of Th1 and Th17 cells to ameliorate experimental autoimmune encephalomyelitis

BACKGROUND: CD4(+) T cells play an important role in the initiation of an immune response by providing help to other cells. Among the helper T subsets, interferon-γ (IFN-γ)-secreting T helper 1 (Th1) and IL-17-secreting T helper 17 (Th17) cells are indispensable for clearance of intracellular as wel...

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Detalles Bibliográficos
Autores principales:	Kang, Youra, Timilshina, Maheshwor, Nam, Tae-gyu, Jeong, Byeong-Seon, Chang, Jae-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330010/ https://www.ncbi.nlm.nih.gov/pubmed/28241881 http://dx.doi.org/10.1186/s40659-017-0113-z

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