Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditions

BACKGROUND: Ischemia and the following reperfusion damage are critical mechanisms of spinal cord injury. Statins have been reported to decrease ischemia–reperfusion injury in many organs including the spinal cord. Anti-oxidative effect is one of the main protective mechanisms of statin against neuro...

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Detalles Bibliográficos
Autores principales: Sohn, Hye-Min, Hwang, Jin-Young, Ryu, Jung-Hee, Kim, Jinhee, Park, Seongjoo, Park, Jin-woo, Han, Sung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330028/
https://www.ncbi.nlm.nih.gov/pubmed/28241838
http://dx.doi.org/10.1186/s13018-017-0536-9

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