Accurate and equitable medical genomic analysis requires an understanding of demography and its influence on sample size and ratio

In a recent study, Petrovski and Goldstein reported that (non-Finnish) Europeans have significantly fewer nonsynonymous singletons in Online Mendelian Inheritance in Man (OMIM) disease genes compared with Africans, Latinos, South Asians, East Asians, and other unassigned non-Europeans. We use simula...

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Detalles Bibliográficos
Autores principales: Kessler, Michael D., O’Connor, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330117/
https://www.ncbi.nlm.nih.gov/pubmed/28241850
http://dx.doi.org/10.1186/s13059-017-1172-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330117/
https://www.ncbi.nlm.nih.gov/pubmed/28241850
http://dx.doi.org/10.1186/s13059-017-1172-8

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