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A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo

Matrix metalloproteinases (MMPs) play a critical role in cancer pathogenesis, including tumor growth and osteolysis within the bone marrow microenvironment. However, the anti-tumor effects of MMPs are poorly understood, yet have significant implications for the therapeutic potential of targeting MMP...

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Detalles Bibliográficos
Autores principales:	Lwin, S. T., Fowler, J. A., Drake, M. T., Edwards, J. R., Lynch, C. C., Edwards, C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330156/ https://www.ncbi.nlm.nih.gov/pubmed/28241871 http://dx.doi.org/10.1186/s12943-017-0616-9

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