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Simulating and optimizing compound refractive lens-based X-ray microscopes
A comprehensive optical description of compound refractive lenses (CRLs) in condensing and full-field X-ray microscopy applications is presented. The formalism extends ray-transfer matrix analysis by accounting for X-ray attenuation by the lens material. Closed analytical expressions for critical im...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330290/ https://www.ncbi.nlm.nih.gov/pubmed/28244432 http://dx.doi.org/10.1107/S160057751602049X |
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author | Simons, Hugh Ahl, Sonja Rosenlund Poulsen, Henning Friis Detlefs, Carsten |
author_facet | Simons, Hugh Ahl, Sonja Rosenlund Poulsen, Henning Friis Detlefs, Carsten |
author_sort | Simons, Hugh |
collection | PubMed |
description | A comprehensive optical description of compound refractive lenses (CRLs) in condensing and full-field X-ray microscopy applications is presented. The formalism extends ray-transfer matrix analysis by accounting for X-ray attenuation by the lens material. Closed analytical expressions for critical imaging parameters such as numerical aperture, spatial acceptance (vignetting), chromatic aberration and focal length are provided for both thin- and thick-lens imaging geometries. These expressions show that the numerical aperture will be maximized and chromatic aberration will be minimized at the thick-lens limit. This limit may be satisfied by a range of CRL geometries, suggesting alternative approaches to improving the resolution and efficiency of CRLs and X-ray microscopes. |
format | Online Article Text |
id | pubmed-5330290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-53302902017-03-01 Simulating and optimizing compound refractive lens-based X-ray microscopes Simons, Hugh Ahl, Sonja Rosenlund Poulsen, Henning Friis Detlefs, Carsten J Synchrotron Radiat Research Papers A comprehensive optical description of compound refractive lenses (CRLs) in condensing and full-field X-ray microscopy applications is presented. The formalism extends ray-transfer matrix analysis by accounting for X-ray attenuation by the lens material. Closed analytical expressions for critical imaging parameters such as numerical aperture, spatial acceptance (vignetting), chromatic aberration and focal length are provided for both thin- and thick-lens imaging geometries. These expressions show that the numerical aperture will be maximized and chromatic aberration will be minimized at the thick-lens limit. This limit may be satisfied by a range of CRL geometries, suggesting alternative approaches to improving the resolution and efficiency of CRLs and X-ray microscopes. International Union of Crystallography 2017-02-20 /pmc/articles/PMC5330290/ /pubmed/28244432 http://dx.doi.org/10.1107/S160057751602049X Text en © Hugh Simons et al. 2017 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/ |
spellingShingle | Research Papers Simons, Hugh Ahl, Sonja Rosenlund Poulsen, Henning Friis Detlefs, Carsten Simulating and optimizing compound refractive lens-based X-ray microscopes |
title | Simulating and optimizing compound refractive lens-based X-ray microscopes |
title_full | Simulating and optimizing compound refractive lens-based X-ray microscopes |
title_fullStr | Simulating and optimizing compound refractive lens-based X-ray microscopes |
title_full_unstemmed | Simulating and optimizing compound refractive lens-based X-ray microscopes |
title_short | Simulating and optimizing compound refractive lens-based X-ray microscopes |
title_sort | simulating and optimizing compound refractive lens-based x-ray microscopes |
topic | Research Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330290/ https://www.ncbi.nlm.nih.gov/pubmed/28244432 http://dx.doi.org/10.1107/S160057751602049X |
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