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Association of 5-hydroxymethylation and 5-methylation of DNA cytosine with tissue-specific gene expression

Differentially methylated or hydroxymethylated regions (DMRs) in mammalian DNA are often associated with tissue-specific gene expression but the functional relationships are still being unraveled. To elucidate these relationships, we studied 16 human genes containing myogenic DMRs by analyzing profi...

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Detalles Bibliográficos
Autores principales: Ponnaluri, V. K. Chaithanya, Ehrlich, Kenneth C., Zhang, Guoqiang, Lacey, Michelle, Johnston, Douglas, Pradhan, Sriharsa, Ehrlich, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330441/
https://www.ncbi.nlm.nih.gov/pubmed/27911668
http://dx.doi.org/10.1080/15592294.2016.1265713