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Conformational diversity analysis reveals three functional mechanisms in proteins
Protein motions are a key feature to understand biological function. Recently, a large-scale analysis of protein conformational diversity showed a positively skewed distribution with a peak at 0.5 Å C-alpha root-mean-square-deviation (RMSD). To understand this distribution in terms of structure-func...
Autores principales: | Monzon, Alexander Miguel, Zea, Diego Javier, Fornasari, María Silvina, Saldaño, Tadeo E., Fernandez-Alberti, Sebastian, Tosatto, Silvio C. E., Parisi, Gustavo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330503/ https://www.ncbi.nlm.nih.gov/pubmed/28192432 http://dx.doi.org/10.1371/journal.pcbi.1005398 |
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