Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice

BACKGROUND: Widely used as a weight loss supplement, trans-10,cis-12 conjugated linoleic acid (10,12 CLA) promotes fat loss in obese mice and humans, but has also been associated with insulin resistance. OBJECTIVE: We therefore sought to directly compare weight loss by 10,12 CLA versus caloric restr...

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Detalles Bibliográficos
Autores principales: den Hartigh, Laura J., Wang, Shari, Goodspeed, Leela, Wietecha, Tomasz, Houston, Barbara, Omer, Mohamed, Ogimoto, Kayoko, Subramanian, Savitha, Gowda, G. A. Nagana, O’Brien, Kevin D., Kaiyala, Karl J., Morton, Gregory J., Chait, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330530/
https://www.ncbi.nlm.nih.gov/pubmed/28245284
http://dx.doi.org/10.1371/journal.pone.0172912

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